Pentamidine dihydrochloride
CAS No. 50357-45-4
Pentamidine dihydrochloride ( MP-601205 dihydrochloride )
产品货号. M27680 CAS No. 50357-45-4
Pentamidine dihydrochloride is an aromatic diamidine agent with activity against a number of microorganisms including protozoa (Trypanosoma brucei, Leishmania spp., and Babesia spp.) and fungi (Pneumocystis jirovecii).
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥405 | 有现货 |
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10MG | ¥608 | 有现货 |
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25MG | ¥1037 | 有现货 |
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50MG | ¥1555 | 有现货 |
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100MG | ¥2325 | 有现货 |
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200MG | ¥3491 | 有现货 |
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500MG | ¥5775 | 有现货 |
|
1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Pentamidine dihydrochloride
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Pentamidine dihydrochloride is an aromatic diamidine agent with activity against a number of microorganisms including protozoa (Trypanosoma brucei, Leishmania spp., and Babesia spp.) and fungi (Pneumocystis jirovecii).
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产品描述Pentamidine dihydrochloride is an aromatic diamidine agent with activity against a number of microorganisms including protozoa (Trypanosoma brucei, Leishmania spp., and Babesia spp.) and fungi (Pneumocystis jirovecii). Pentamidine dihydrochloride is a potent and selective protein tyrosine phosphatases and phosphatase of regenerating liver inhibitor. Pentamidine dihydrochloride inhibits parasite Leishmania infantum with an IC50 of 2.5 μM.(In Vitro):Pentamidine at its therapeutic doses inhibited recombinant PRL phosphatases in vitro and inactivated ectopically expressed PRLs in NIH3T3 transfectants with an effective duration more than 24 h after a pulse cell treatment.(In Vivo):Pentamidine at a tolerable dose markedly inhibited the growth of WM9 human melanoma tumors in nude mice coincident with the induction of tumor cell necrosis and is capable of inactivating ectopically expressed PRL-2 in the cancer cells.
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同义词MP-601205 dihydrochloride
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通路Metabolic Enzyme/Protease
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靶点Phosphatase
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受体aryl hydrocarbon receptor;GSK-3;CDK1/CyclinB;CDK5/p25
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研究领域——
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适应症——
化学信息
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CAS Number50357-45-4
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分子量413.3
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分子式C19H26Cl2N4O2
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纯度>98% (HPLC)
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溶解度——
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SMILES[Cl-].[Cl-].NC(=[NH2+])c1ccc(OCCCCCOc2ccc(cc2)C(N)=[NH2+])cc1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Meijer L, et al. GSK-3-selective inhibitors derived from Tyrian purple indirubins. Chem Biol. 2003 Dec;10(12):1255-66.
产品手册
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